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Thread: Ok, so I'm always looking into anti-aging research.

  1. #1
    i am an old friend of ytcracker's betticus's Avatar
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    Default Ok, so I'm always looking into anti-aging research.

    And I've found a very interesting article on the role of ... well, it's a pretty easy read compared to a lot of the stuff so give it a look.

    http://grove.ufl.edu/~cleeuwen/mtapoptosis.htm

    Summary:

    Programmed cell death has received phenomenal attention in the past few years. It is now known that mitochondria play a central regulatory role in apoptosis, particularly through the cytochrome c pathway. Also, mitochondria and radical species are intimately involved in the programmed cell death that occurs during aging and exercise. Increased oxidative stress from ROS and RNS changes the cellular redox potentials, depletes glutathione, and decreases reducing equivalents like NADP and NADPH. These intracellular changes are sufficient to induce the formation of mitochondrial permeability transition pores, leading to the subsequent release of cytochrome c and the activation of the caspase cascade. We hypothesize that during chronic conditions of oxidative stress as in aging, tissues may undergo unnecessary and increased apoptosis, leading to pathological dysfunctions from significant cell loss. Similarly, uncontrolled and unnecessary apoptosis may occur during exhaustive exercise resulting in various pathologies.
    Last edited by betticus; 10-17-2008 at 05:57 AM.

  2. #2
    leon's Avatar
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    Yeah.

    Scientist Itt.
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  3. #3
    i am an old friend of ytcracker's betticus's Avatar
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    Cliffs: Moderate exercise helps to protect your body from aging while strenuous exercise accelerates aging.

  4. #4
    i am an old friend of ytcracker's betticus's Avatar
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    And all this time I thought that you guys were super geniuses. This is only around a sixth grade reading level.

  5. #5

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    Quote Originally Posted by betticus View Post
    And all this time I thought that you guys were super geniuses. This is only around a sixth grade reading level.
    Welcome to my world (although it was PimpLeon who commented). good read. Srsly the hardest word is apoptosis and only because its a technical term. Mitochondria should be known by all, etc.

    Sex is moderate exercise and can help keep you healthy. 15 minutes of sex 3x/wk is equivalent to running a bunch. even walking a mile a day is great.

    This is why people fall for Kinoki footpads.
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  6. #6
    i am an old friend of ytcracker's betticus's Avatar
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    There is a shitload of info out there but you have to hunt it down and tie the studies together yourself.

    Skeletal muscle tissue isn't the problem unless you work out hard enough to tear em up to the point where you are stiff and sore for days. Working out so lightly that you don't stress the tissue isn't the goal either. You have to go hard enough to stress the bone so that you don't end up suffering from osteoporosis later on. Human clinical trials and long term studies are hard to come by though. Even with a group of volunteers you have to rely on them to follow the programs exactly and most people simply won't do it.

    Short of using prisoners but for some reason that's considered to be inhumane.

  7. #7

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    It would be nice if we could simply stop time. I hate time. I really honestly hate time. I really could do without time.

  8. #8
    i am an old friend of ytcracker's betticus's Avatar
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    Time control would be sweet. I would have so many do-overs.

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